abstract：:BACKGROUND The factors associated with osteoporosis are poorly understood in the Chinese population. This study aimed to examine the factors associated with osteoporosis and with fractures in a Chinese elderly population. MATERIAL AND METHODS This was a cross-sectional study of elderly people living in Tianjin between...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang Y,Ding H,Wang X,Wei Z,Feng S

更新日期：2019-07-27 00:00:00

abstract：:BACKGROUND Ultrasonography of the diaphragm is an under-utilized instrument in cervical spinal cord injury patients. We conducted a pilot study to first compare the difference of diaphragm thickness and the excursion between patients with cervical spinal cord injury and healthy volunteers, and second to correlate diap...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Z,Li J,Yang D,Du L,Yang M

更新日期：2019-07-20 00:00:00

abstract：:BACKGROUND Osteoporosis is a common osteopathy, resulting in fractures, especially in elder people. Sesamin has many pharmacological effects, including supplying calcium. However, how sesamin might prevent osteoporosis is still under study. MATERIAL AND METHODS Bone marrow stromal cells (BMSCs) extracted from rat femu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ma ZP,Zhang ZF,Yang YF,Yang Y

更新日期：2019-07-17 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the association between body mass index (BMI) and brachial-ankle pulse wave velocity (baPWV) in hypertensive males. MATERIAL AND METHODS Altogether, 14 866 male hypertensive participants were included in the analysis. Participants were divided into 3 groups: low BMI ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang J,Chen Z,Yuan J,Zhang C,Chen H,Wu W,Chen Z,Liu Y,Zheng M,Chen S,Wu S,Chen Y

更新日期：2019-07-15 00:00:00

abstract：:BACKGROUND This study aimed to investigate the association between the rs2975760 and rs3792267 single nucleotide polymorphisms (SNPs) of the calpain 10 (CAPN10) gene and gestational diabetes mellitus. MATERIAL AND METHODS The study included 138 patients with gestational diabetes mellitus and 152 healthy pregnant women...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang X,Shi C,Wei L,Sun F,Ji L

更新日期：2019-07-11 00:00:00

abstract：:BACKGROUND Curcumin is an antioxidant that reduces inflammation and pain. This study aimed to assess the effect of pretreatment with naproxen and liposomal curcumin compared with naproxen and curcumin solution on oxidative stress parameters and pain in a rat model of migraine. MATERIAL AND METHODS Sixty-three male Wis...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bulboacă AE,Bolboacă SD,Bulboacă AC,Porfire AS,Tefas LR,Suciu ȘM,Dogaru G,Stănescu IC

更新日期：2019-07-09 00:00:00

abstract：:BACKGROUND This study aimed to examine the effects of the sesquiterpene lactone, parthenolide, on migration, autophagy, and apoptosis of MDA-T32 human papillary thyroid carcinoma cells in vitro and in mouse tumor xenografts. MATERIAL AND METHODS Cell proliferation and viability...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li C,Zhou Y,Cai Y,Shui C,Liu W,Wang X,Jiang J,Zeng D,Gui C,Sun R

更新日期：2019-07-08 00:00:00

abstract：:BACKGROUND Inappropriate use of antibiotics results in antimicrobial resistance and dysbacteriosis. Among critically ill cirrhotic patients, consensus regarding the most optimal prescription strategy for antibiotics use has not been achieved. For these patients, the score for end-stage liver disease (MELD) demonstrate...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou YF,Zhou YJ,Ye FZ,Liu WY,Zheng MH

更新日期：2019-07-06 00:00:00

abstract：:BACKGROUND We assessed the relationship between body mass index and results of rehabilitation in stroke patients. MATERIAL AND METHODS The study was carried out at the Clinical Rehabilitation Ward with Early Neurological Rehabilitation Unit at the Clinical Hospital. The examinations were performed 3 times. Based on in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Leszczak J,Czenczek-Lewandowska E,Przysada G,Baran J,Weres A,Wyszyńska J,Mazur A,Kwolek A

更新日期：2019-07-01 00:00:00

abstract：:BACKGROUND Results of the landmark Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) trial comparing rhythm control and rate control strategies has led to dramatic changes in the pharmacological management of non-valvular atrial fibrillation (NVAF) patients. We sought to investigate the effect ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hou XX,Du X,Zheng D,Li YM,He L,Li XX,Dong JZ

更新日期：2019-06-30 00:00:00

abstract：:BACKGROUND Klatskin tumor (KCC) is a rare type of tumor, with an annual incidence rate of no more than 1: 100 000. Because of its rarity, KCC is difficult to investigate. The present study provides new insights into KCC by a using public database. MATERIAL AND METHODS We used the Surveillance, Epidemiology, and End Re...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang X,Liu H

更新日期：2019-06-17 00:00:00

abstract：:This article is retracted due to authors' claims in regards to errors in data and statistical analyses. Authors' message: We greatly regret to inform you that we just discovered some fatal errors in the statistical analysis, in which we mistakenly used the cultured cells TCR sequencing data as the results of CD8+ LAG3...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang L,Qiao G,Wu J,Ren J

更新日期：2019-06-13 00:00:00

abstract：:BACKGROUND This study aimed to investigate the factors associated with sarcopenia in elderly residents in three nursing homes in Suzhou City, East China including the association with nutrition and physical exercise. MATERIAL AND METHODS Elderly residents (n=316) from three nursing homes included 112 men and 204 women...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yang LJ,Wu GH,Yang YL,Wu YH,Zhang L,Wang MH,Mo LY,Xue G,Wang CZ,Weng XF

更新日期：2019-06-13 00:00:00

abstract：:BACKGROUND Previous studies have shown that exocyst complex is located at polarized growth sites at different cell cycle stages in budding yeast. But how cell cycle and the cyclin-dependent kinase, Cdk1, regulate the distribution of exocyst complex on the plasma membrane and the protein level of each exocyst subunit i...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang T,Sun D,Luo G,Liu Y

更新日期：2019-05-31 00:00:00

abstract：:BACKGROUND The ADRB2 gene encodes the ß2-adrenergic receptor (ß2-AR). This study aimed to determine the association between the C79G polymorphism of the ADRB2 gene and its association with pediatric asthma using a meta-analysis of the published data. MATERIAL AND METHODS Review of publications up to May 2018 was from ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang YQ,Zhu KR

更新日期：2019-05-30 00:00:00

abstract：:BACKGROUND The aim of this study was to analyze the relative expression level of miR-30d-5p, miR-23a-3p, and miR-146a-5p, and to comprehensively assess the diagnostic and predictive possibilities of these miRNAs. Their expression changes have not yet been sufficiently investigated during acute myocardial infarction. T...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bukauskas T,Mickus R,Cereskevicius D,Macas A

更新日期：2019-05-27 00:00:00

abstract：:BACKGROUND This study aimed to undertake an analysis of ten years of real-world evidence (RWE) on overall survival (OS) following treatment of advanced gastrointestinal stromal tumor (GIST) with imatinib, sunitinib, and sorafenib using data from the Polish National Health Fund. MATERIAL AND METHODS Data from the Polis...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Brzozowska M,Wierzba W,Szafraniec-Buryło S,Czech M,Połowinczak-Przybyłek J,Potemski P,Śliwczyński A

更新日期：2019-05-23 00:00:00

abstract：:BACKGROUND The purpose of the present study was to investigate the function and mechanism of dihydroartemisinin (DHA) in treating ovalbumin-induced asthma in BALB/c mice. MATERIAL AND METHODS Thirty female BALB/c mice were randomly separated into 3 groups: the control group, the asthma model group stimulated by ovalbu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu H,Ji W

更新日期：2019-05-22 00:00:00

abstract：:BACKGROUND Sesquiterpene lactones have gained tremendous attention owing to their potent anticancer properties. The main focus of this study was to evaluate the anticancer effects of a naturally occurring sesquiterpene lactone, santonin, against human breast cancer SK-BR-3 cells. MATERIAL AND METHODS Cell counting kit...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu Z,Wang C,Huang M,Tao Z,Yan W,Du Y

更新日期：2019-05-18 00:00:00

abstract：:BACKGROUND Senescence is a natural barrier for the body to resist the malignant transformation of its own cells. This work investigated the senescence characteristics of cancer cells in vitro. MATERIAL AND METHODS Human cervical cancer HeLa cells were treated with different concentrations of doxorubicin for 3 days, wi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hu X,Zhang H

更新日期：2019-05-16 00:00:00

abstract：:BACKGROUND This study aimed to use gas chromatography-mass spectrometry (GC-MS) to identify the chemical constituents of volatile oil extracted by steam distillation from Cichorium glandulosum Boiss et Huet (CG), a traditional Uyghur medicine, and to investigate its effects on carbon tetrachloride (CCl₄)-induced hepat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qin DM,Wang XB,Zou N,Han C,Xu J

更新日期：2019-05-15 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the role of deubiquitinase [ovarian tumor domain-containing protein 5 (OTUD5)] in regulating Akt ubiquitination and its effect on the radiosensitivity of cervical cancer. MATERIAL AND METHODS Cervical cancer C33A cells were cultured, and then 2 groups of cells (overe...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yin F,He H,Zhang B,Zheng J,Wang M,Zhang M,Cui H

更新日期：2019-05-10 00:00:00

abstract：:BACKGROUND The protein 4.1 family is a family of cytoskeletal proteins that play an important role in maintaining normal cell morphology and cell adhesion, migration, division, and intercellular signaling. The main aim of this study was to explore the prognostic significance of the protein 4.1 family in breast cancer ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Feng G,Guo K,Yan Q,Ye Y,Shen M,Ruan S,Qiu S

更新日期：2019-05-07 00:00:00

abstract：:BACKGROUND Catheter radiofrequency ablation for typical atrial flutter is considered to be safe and effective. However, atrial fibrillation (AF) following cavotricuspid isthmus ablation for atrial flutter has been reported in patients without a previous history of AF, which has implications for the decision to use ora...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Warchoł I,Bińkowski BJ,Kucejko T,Sobiczewska J,Lubiński A

更新日期：2019-05-05 00:00:00

abstract：:BACKGROUND Mirror therapy for stroke patients was reported to be effective in improving upper-extremity motor function and daily life activity performance. In addition, game-based virtual reality can be realized using a gesture recognition (GR) device, and various tasks can be presented. Therefore, this study investig...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Choi HS,Shin WS,Bang DH

更新日期：2019-05-03 00:00:00

abstract：:BACKGROUND Fertility preservation is very important for male cancer patients, especially adolescents. Unfortunately, the use of fertility preservation is very low among Chinese male cancer patients. Additionally, the cumulative rate of frozen sperm use is also low. MATERIAL AND METHODS We performed a retrospective stu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Fu L,Zhou F,An Q,Zhang K,Wang X,Xu J,Guo Y,Lu W,Liang X,Gu Y

更新日期：2019-05-03 00:00:00

abstract：:BACKGROUND The objective of this paper was to assess the complications following sentinel lymph node biopsy (SLNB) in breast cancer patients using the SentiMag® method. MATERIAL AND METHODS The study material consisted of 368 patients who had received the SLNB procedure in combination with wide local excision (WLE), s...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lorek A,Stojčev Z,Zarębski W,Kowalczyk M,Szyluk K

更新日期：2019-04-29 00:00:00

abstract：:BACKGROUND Diabetic nephropathy (DN) is a potentially fatal complication of diabetes mellitus. While lifestyle changes can reduce diabetes risk, it is unclear whether improved lifestyle can slow or reverse DN progression. This study evaluated whether an intensive lifestyle intervention (IL-I) targeting weight loss and...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dong L,Li J,Lian Y,Tang ZX,Zen Z,Yu P,Li Y

更新日期：2019-04-25 00:00:00

abstract：:BACKGROUND T follicular helper (Tfh) cells are a subgroup of activated CD4+ T cells in the germinal centers of secondary lymphoid organs, they play critical roles in the development of many chronic autoimmune inflammatory diseases. The aim of this study was to investigate whether circulating Tfh cells contribute to th...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cao G,Chi S,Wang X,Sun J,Zhang Y

更新日期：2019-04-25 00:00:00

abstract：:BACKGROUND Pancreatic cancer is a major cause of mortality worldwide. Inefficient drugs, their adverse effects, and the development of drug resistance make it difficult to curb the growing incidence of pancreatic cancer. Against this backdrop, the development new drug regimens with no or negligible adverse effects is ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Fang K,Wang L,Chen L,Liu T,Fang Z

更新日期：2019-04-21 00:00:00

abstract：:Worldwide, metastatic melanoma of the skin has an aggressive course with high morbidity and mortality. Therefore, an increased understanding of the pathogenesis of metastatic melanoma has gained increasing attention, including the role of epigenetic modification and competing endogenous RNA (ceRNA). This study aimed t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang LX,Wan C,Dong ZB,Wang BH,Liu HY,Li Y

更新日期：2019-04-20 00:00:00

abstract：:BACKGROUND lncRNA BANCR participates in the pathogenesis of various types of human diseases; however, its involvement in diabetic retinopathy is unknown. MATERIAL AND METHODS In this study, the expression of lncRNA BANCR in plasma of patients with diabetic retinopathy, diabetic patients without complications, and heal...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yin L,Sun Z,Ren Q,Su X,Zhang D

更新日期：2019-04-18 00:00:00

abstract：:BACKGROUND The prevalence of chronic pain among the elderly is high (estimated at 25-85%) and may adversely affect their everyday functioning, although it is often unrecognized. MATERIAL AND METHODS The aim of this study was to assess the prevalence of chronic pain, especially with th...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Stompór M,Grodzicki T,Stompór T,Wordliczek J,Dubiel M,Kurowska I

更新日期：2019-04-12 00:00:00

abstract：:BACKGROUND Reports show that ultrasound-targeted microbubble destruction (UTMD) is a promising method of gene therapy, and metadherin (MTDH) is related to the development of breast cancer. Thus, we investigated the role of MTDH in breast cancer and compared the effect of suppressing MTDH by shRNA using liposome, UTMD,...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu J,Wang Y,Li Z,Wang Q,Zhou X,Wu W

更新日期：2019-04-10 00:00:00

abstract：:BACKGROUND More and more recent studies have clearly shown that long non-coding RNA (lncRNA) should be considered as a fundamental part of the ceRNA network, mainly because lncRNA can act as miRNA sponges to regulate the protein-coding gene expression. Nevertheless, it is still not clear how lncRNA-mediated ceRNAs fun...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen W,Chen X,Wang Y,Liu T,Liang Y,Xiao Y,Chen L

更新日期：2019-04-09 00:00:00

abstract：:BACKGROUND The disordered metabolism of liver function in liver cancer patients can affect postoperative survival after liver transplantation. We assessed whether the levels of various chemicals in liver metabolism prior to receiving a liver transplant were prognostic factors and metabolism markers in predicting survi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li X,Gong J,Zhou W,Zhang H,Zheng J,Liang J,Hu B

更新日期：2019-04-01 00:00:00

abstract：:BACKGROUND Spinal manipulation, particularly in cervical rotatory manipulation (CRM), has become increasingly popular in physical therapies, with satisfying effect. However, it is still unclear whether CRM affects internal carotid arteries (ICA) with mild carotid atherosclerosis (CAS), especially in hemodynamics. MATE...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guan T,Zeng Y,Qi J,Qin B,Fu S,Wang G,Zhang L

更新日期：2019-03-31 00:00:00

abstract：:Bacterial meningitis has a high mortality rate and can be challenging to diagnose and manage. This study aimed to evaluate the effect of diosmetin in a rat model of Streptococcus pneumoniae meningitis and to investigate the mechanism of action. Forty rats included a treatment group (n=30) that underwent intracisternal...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Y,Jiang Y,Lu D

更新日期：2019-03-27 00:00:00

abstract：:BACKGROUND Doxorubicin (DOX) is a potent chemotherapeutic agent used to treat colon cancer. Despite impressive initial clinical responses, drug resistance has dramatically compromised the effectiveness of DOX. However, the underlying mechanisms of chemotherapeutic resistance in colon cancer remain poorly understood. M...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang H,Deng Z,Chen X,Cai J,Ma T,Zhong Q,Li R,Li L,Li T

更新日期：2019-03-24 00:00:00

abstract：:BACKGROUND Endothelial injury is the main mechanism of atherosclerosis, and is caused by oxidized low-density lipoprotein (ox-LDL). Astragaloside IV (AS-IV) is the primary active ingredient of the Chinese herb Huangqi, and exhibits antioxidant and anti-inflammatory properties in cardiovascular diseases. This study inv...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Z,Li J,Zhang X

更新日期：2019-03-22 00:00:00